TISSUE CONCENTRATION OF INTRAVESICALLY INSTILLED (2^|^Prime;R)-4^|^prime;-0-TETRAHYDROPYRANYL-ADRIAMYCIN OR ADRIAMYCIN IN SUPERFICIAL BLADDER CANCER
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منابع مشابه
Tissue concentration of doxorubicin (adriamycin) in mouse pretreated with alpha-tocopherol or coenzyme Q10.
The tissue concentration of doxorubicin (adriamycin; ADM) and its major metabolite (aglycone I) was examined in mice pretreated with alpha-tocopherol (VE) or coenzyme Q10 (CoQ). In VE-pretreated group, the concentrations of aglycone I of the liver (1, 3 and 5 h after the administration), kidney (1 and 3h) and heart (3h) were significantly higher than those in the saline group. The clinical appl...
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The aim of this study is to evaluate the effects of pravastatin on Adriamycin (ADR)-induced nephropathy and the mechanisms involved. Forty rats were divided into the following 4 groups: control, ADR (15 mg.kg-1, IP), ADR plus pravastatin (20 mg.kg-1 which was started 5 days prior to ADR injection), and ADR plus pravastatin (20 mg.kg-1 which was started 5 days after ADR injection). On day 20 aft...
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متن کاملFT- SERS Study of Adriamycin - DNA Intraction
FT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 suggests that ring D of adriamycin is not involved in the intercalation process.
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1993
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol1989.84.1206